Common Genetic Etiologies and Biological Pathways Shared Between Autism Spectrum Disorders and Intellectual Disabilities
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منابع مشابه
Molecular mechanisms of cognitive and behavioral comorbidities of epilepsy in children.
Intellectual and developmental disabilities (IDDs) such as autistic spectrum disorders (ASDs) and epilepsies are heterogeneous disorders that have diverse etiologies and pathophysiologies. The high rate of co-occurrence of these disorders, however, suggests potentially shared underlying mechanisms. A number of well-known genetic disorders share epilepsy, intellectual disability, and autism as p...
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The discovery of the genetic causes of syndromic autism spectrum disorders and intellectual disabilities has greatly informed our understanding of the molecular pathways critical for normal synaptic function. The top-down approaches using human phenotypes and genetics helped identify causative genes and uncovered the broad spectrum of neuropsychiatric features that can result from various mutat...
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Abstract Backgrounds: When a child has a developmental disability, the parenthood stress can be onerous. Research on the parenting stress has addressed the parenting stress differences between children families with and without disabilities. The purpose of the current research was to examine the comparison of parenting related stress and depression symptoms in mothers of children recently diagn...
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Autistic spectrum disorders (ASD) and epilepsies are heterogeneous disorders that have diverse etiologies and pathophysiologies. The high rate of co-occurrence of these disorders suggest potentially shared underlying mechanisms. A number of well-known genetic disorders share epilepsy and autism as prominent phenotypic features, including tuberous sclerosis, Rett syndrome, and fragile X. In addi...
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Background: Autism Spectrum Disorder (ASD) is a devastating, developmental disease and has several significant impacts on the patient’s life: impairment in social interactions as in both verbal and nonverbal behaviors, failing to develop relationships and respond to normal teaching methods, intellectual disabilities, and repetitive behaviors, being unable to instinctively ...
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